发布日期：20100906

鐢熸畺鍣ㄧ柋鐤圭殑缁嗚優鍏嶇柅鍙婂厤鐤不鐤楃幇鐘--銆婂箔鍗楃毊鑲ゆх梾绉戞潅蹇椼2005骞03鏈
鐢熸畺鍣ㄧ柋鐤圭殑缁嗚優鍏嶇柅鍙婂厤鐤不鐤楃幇鐘
骞夸笢鐪佷腑鍖婚櫌鐨偆绉 骞夸笢骞垮窞510120 (閮戞瘏鏄 骞夸笢鐪佷腑鍖婚櫌鐨偆绉 骞夸笢骞垮窞510120(绂ゅ浗缁)
銆怐OI銆戯細cnki:ISSN:1009-8968.0.2005-03-037
銆銆鐢熸畺鍣ㄧ柋鐤(genital herpes,GH)鏄敱鍗曠函鐤辩柟鐥呮瘨II鍨(herpes simplex virus II,HSV-II)鎰熸煋鐢熸畺鍣ㄩ儴浣嶇毊鑲ょ矘鑶滄墍寮曡捣鐨勭値鐥囥佹按鐤便佹簝鐤℃х柧鐥匸1],鏄竴绉嶅父瑙佺殑闅炬不鎰堢殑鎬т紶鎾柧鐥,闅忕潃鎬т紶鎾柧鐥呭彂鐥呯巼涓婂崌鑰岄愭笎澧炲銆傝鐥呭鍙戠巼楂,鍦ㄥコ鎬у彲寮曡捣涓嶅瓡銆佹祦浜ф垨鏂扮敓鍎挎浜°傝
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呮不鐤楀墠鍚庡鍛ㄨT缁嗚優浜氱兢鐨勬娴
閲嶇粍浜哄共鎵扮礌伪-2b涔宠啅娌荤枟甯︾姸鐤辩柟鍜岀敓娈栧櫒鐤辩柟 [J];澶ц繛鍖荤澶у瀛︽姤; 2003骞03鏈
瀛ｅ崏,鏉庡瘜鑽,绔ョ鐢,鎴挎濆畞,鏉滄檽绾,榄忎附铏,鐜嬫柊鏍; 澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呴粡闄勫垎瀛怚CAM-1銆丩-閫夋嫨绱犲拰P-閫夋嫨绱犵殑琛ㄨ揪
鍗℃彁绱犲拰骞叉壈绱犳不鐤楀鍙戞х敓娈栧櫒鐤辩柟鐤楁晥瑙傚療 [J];涓浗楹婚鐨偆鐥呮潅蹇; 2003骞06鏈
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呰娓匢L-2/IFN-纬姘村钩鍜孨K/LAK缁嗚優娲绘х殑鍙樺寲
閲嶇粍骞叉壈绱犖-2b涓嶅悓缁欒嵂鏂瑰紡娌荤枟鐢锋у鍙戞х敓娈栧櫒鐤辩柟鐨勭枟鏁堟瘮杈 [J];涓村簥鐨偆绉戞潅蹇; 2002骞03鏈
杞Щ鍥犲瓙瀵瑰鍙戞х敓娈栧櫒鐤辩柟鎮ｈ匱缁嗚優浜氱兢鏀瑰彉鐨勮皟鑺傛晥搴
鏁栦繆绾!100700,鍛ㄧぜ涔,闄堝叴骞,鏉ㄨ搲濞!100700,寮犳按鏂!100700,鏉庡ぇ浼!100700; 鐢熸畺鍣ㄧ柋鐤规偅鑰呭崟涓鏍哥粏鑳炲垎娉岃偪鐦ゅ潖姝诲洜瀛愇便佺櫧浠嬬礌6鍜孒LA-鈪＄被鎶楀師琛ㄨ揪鐨勭爺绌 [J];涓崕鐨偆绉戞潅蹇; 2000骞06鏈
閭撲簯鍗,闄堝叴骞,璁告垚钃,闄堟槧鐜; 澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨ鍗曚竴鏍哥粏鑳濩D40鍜孋D40L鐨勮〃杈 [J];涓崕鐨偆绉戞潅蹇; 2004骞05鏈
Tyring SK, Cariton SS, Evans T; Herpes Atypical clinical manifestations
Auvert B, Ballard R, Campbell C, et al; HIV infection among youth in a South African m ining town is associated with herpes simplex virus-2 Seropositivity and sexual behaviour
D iehl L, Den BoerAT, van derVoortEI, et al; The role of CD40 in peripheral T cell tolerance and immunity
Genital herpes Simplex virus infection [M];Med clin NorthAm; 1990骞
Lissoni P, Barni, Rovelli F, et al; The biological significance of soluble interleukin -2 receptors in solid tumors
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨCD4~+CD25~+Foxp3~+璋冭妭鎬缁嗚優鐨勬娴 [J];涓崕鐨偆绉戞潅蹇; 2006骞12鏈
闃挎様娲涢煢鑱斿悎涓嵂鎶楃梾姣掗绮掓不鐤楃敓娈栧櫒鐤辩柟
Th1/Th2缁嗚優鍥犲瓙涓庣敓娈栧櫒鐤辩柟鍏崇郴鐨勭爺绌剁幇鐘 [J];鍥介檯鐨偆鎬х梾瀛︽潅蹇; 2006骞01鏈
姣嶇墰鍒嗘敮鏉嗚弻鑿岃嫍鑱斿悎闃挎様娲涢煢娌荤枟澶嶅彂鎬х敓娈栧櫒鐤辩柟鐤楁晥瑙傚療
闃缓娉,閭撴晱鑺,鏈辩憺娓,鏈卞拰鐜,閮戞枃浜,寮犻湠; 鍜柟鑾壒鑱斿悎涓囦箖娲涢煢鎺у埗鐢熸畺鍣ㄧ柋鐤瑰鍙戠殑鎺㈣ [J];璧ｅ崡鍖诲闄㈠鎶; 2005骞06鏈
鑷嫙鎵舵璐ユ瘨姹ら闃插鍙戞х敓娈栧櫒鐤辩柟澶嶅彂鐤楁晥瑙傚療 [J];涓尰鑽复搴婃潅蹇; 2006骞01鏈
鏉庣幉 ,涓ュ湥 ,闄堝皬鐞 ,鑳″环涔; IL-2涓庝竾涔冩礇闊﹁仈鍚堟不鐤95渚嬪鍙戞х敓娈栧櫒鐤辩柟鐤楁晥瑙傚療 [J];绂忓缓鍖昏嵂鏉傚織; 2002骞01鏈
瀛斿簡娉,闄堣繘鍐,闄堝痉鍧,寮犲溅鏄; 涓ょ杞Щ鍥犲瓙瀵圭姮澶栧懆琛T缁嗚優浜氱兢鐨勫奖鍝 [J];涓浗鐣滅墽鍏藉尰; 2007骞07鏈
骞叉壈绱犲眬閮ㄦ敞灏勫姞闃挎様娲涢煢娌荤枟澶嶅彂鎬х敓娈栧櫒鐤辩柟49渚
[J];璧ｅ崡鍖诲闄㈠鎶; 2006骞06鏈
涓タ鍖荤粨鍚堟不鐤楀鍙戞х敓娈栧櫒鐤辩柟鐨勪复搴婄爺绌
鐚佺姮杞Щ鍥犲瓙瀵圭姮缁嗚優鍏嶇柅褰卞搷鐨勬瘮杈冪爺绌
鐤辩柟鍑娌荤枟澶嶅彂鎬х敓娈栧櫒鐤辩柟鐨勪复搴婄爺绌
閲嶇粍浜哄共鎵扮礌伪澶栫敤娌荤枟鐢熸畺鍣ㄧ柋鐤逛复搴婅瘯楠
鐚浆绉诲洜瀛愭敞灏勬恫瀵圭敓闀跨尓鍏嶇柅鍔熻兘褰卞搷鐨勭爺绌
RGH鎮ｈ呯劍铏戙佹姂閮佺浉鍏冲洜绱犲拰鑲濋儊璇佺殑璋冩煡
杞Щ鍥犲瓙澧炲己鐘粏鑳炲厤鐤姛鑳界殑浣滅敤鏈虹悊鐮旂┒
涓嵂鎶楃梾姣掕兌鍥婂RGH鎮ｈ呯敓瀛樿川閲忕殑褰卞搷鍙婃姉HSV-2娼滀紡鎰熸煋鐨勫疄楠岀爺绌
[A];棣栧眾璧ｉ剛婀樹腑瑗垮尰缁撳悎锛堢敓娈栧唴鍒嗘硨锛夊鏈爺璁ㄤ細璁烘枃闆 [C]; 2006骞
涓ょ杞Щ鍥犲瓙瀵圭姮澶栧懆琛T缁嗚優浜氱兢褰卞搷鐨勬瘮杈 [A];涓浗鐣滅墽鍏藉尰瀛︿細鍏荤姮瀛﹀垎浼氱鍗佷簩娆″叏鍥藉吇鐘鏈爺璁ㄤ細璁烘枃闆 [C]; 2007骞
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨCD3~+T缁嗚優鍐呯粏鑳炲洜瀛愮殑妫娴 [J];涓崕鐨偆绉戞潅蹇; 2001骞03鏈
Fontenot JD, Rasmussen JP, Williams LM, et al; Regulatory T cell lineage specification by the forkhead transcription factor foxp3
Sakaguchi S, Sakaguchi N, Asano M, et al; Immunologic self- tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25 Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
Nagler-Anderson C, Bhan AK, Podolsky DK, et al; Control freaks: immune regulatory cells
Roncador G, Brown PJ, Maestre L, et al; Analysis of FOXP3 pro- tein expression in human CD4+CD25+ regulatory T cells at the single-cell level [M];Eur J Immunol; 2005骞
Suvas S, Kumaraguru U, Pack CD, et al; CD4+CD25+ T cells reg- ulate virus-specific primary and memory CD8+ T cell responses
Nakamura K, Kitani A, Fuss I, et al; TGF-beta 1 plays an impor- tant role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice
Huber S, Schramm C, Lehr HA, et al; Cutting edge: TGF-beta sig- naling is required for the in vivo expansion and immunosuppres- sive capacity of regulatory CD4+CD25+ T cells
Chen W, Jin W, Hardegen N, et al; Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
IL-10鐨勭爺绌惰繘灞:涓庡嚑绉嶇柧鐥呯殑鐩稿叧鎬 [J];鍥藉鍖诲.鍏嶇柅瀛﹀垎鍐; 1999骞04鏈
ICAM-1铔嬬櫧鍜宮RNA鍦ㄦ參鎬т箼鍨嬭倽鐐庤倽缁勭粐涓殑琛ㄨ揪 [J];绗笁鍐涘尰澶у瀛︽姤; 2000骞03鏈
鐢熸畺鍣ㄧ柋鐤圭殑棰勯槻涓庢帶鍒垛斺旈棶棰樺拰瀵圭瓥 [J];鍥藉鍖诲.鐨偆鎬х梾瀛﹀垎鍐; 1997骞02鏈
[J];鍥藉鍖诲.鐨偆鎬х梾瀛﹀垎鍐; 1998骞01鏈
鏃犵幆楦熻嫹鍔犲共鎵扮礌娌荤枟澶嶅彂鎬х敓娈栧櫒鐤辩柟40渚嬬枟鏁堣瀵 [J];涓村簥鐨偆绉戞潅蹇; 1999骞04鏈
澶嶅彂鎬х敓娈栧櫒鐤辩柟鐥呬汉琛娓呯櫧缁嗚優浠嬬礌2姘村钩鐨勭爺绌 [J];涓村簥鐨偆绉戞潅蹇; 1995骞04鏈
閭撴爲妫,闃缓娉,闃編鏋,闄堣壋鐝,闄堝浗鏁; 45渚嬬敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨT娣嬪反缁嗚優浜氱兢鍙妔IL-2R姘村钩鐨勬娴嬬粨鏋 [J];宀崡鐨偆鎬х梾绉戞潅蹇; 1998骞03鏈
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨT娣嬪反缁嗚優CD69鍜孒LA-DR鐨勮〃杈 [J];涓崕鐨偆绉戞潅蹇; 2004骞05鏈
椹櫨鑺!253014,鍚存窇鍏!253014,寮犵孩姊!253014,瀹嬫墽鏁!253014,钖涗竾鍗!253014; 鐢熸畺鍣ㄧ柋鐤规偅鑰呰娓卻IL2R姘村钩鍙奛K缁嗚優娲绘ф祴瀹 [J];涓崕鐨偆绉戞潅蹇; 1998骞03鏈
Interleukin l-dependent induction of both interleukin 2 secretion and interleukin 2 receptor expression by thymona cells
Inagaki K, Daikoku T, Goshima F, et al; Impaired induction of protective immunity by highly virulent herpes simplex virus type 2 in a murine model of genital herpes
Tietz W, Allemand Y, Borges E, et al; CD4+ T cells immigrate into inflamed skin only if they express ligands for E-and P-selectin
Daling JR, Madeleine MM, Mcknight B, et al; The relationship of human papillomavirus-related cervical tumors to cigarette smoking, oral contraceptive use, and prior herpes simplex virus type 2 infection [M];Cancer Epidemiol Biomarkers Prev; 1996骞
Tran EH, Prince EN, Owens T; IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines
Roles of different T-cell subsets in control of herpes simplex virus infection determined by using T-cell-deficient mouse-models
Inhibition of invitro adherence of antibody- coated red cells to monocytes by the dialyzable leukocyte extract
Shupack J, Stiller M, Davis I, et al; Topical alpha-interferon ointment with dimethyl sulfoxide in the treatment of recurrent genital herpes simplex
Sad S, Marcotte R, Mosmann TR; Cytokine-induced differentiation of precursor mouse CD8+ T cell into cytotoxic CD8+ T cells secreting Th1 or Th2 cytokines
Sin JI, Kim JJ, Boyer JD, et al; In vivo modulation of vaccine-induced immune responses toward a Th1 phentype increase potency and vaccine effectiveness in a herpes simplex virus type 2 mouse model
鐢熸畺鍣ㄧ柋鐤规偅鑰呮棤鐥囩姸HSV鎺掓硨鐮旂┒杩涘睍
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨT缁嗚優浜氱兢鍜孨K缁嗚優妫娴嬪垎鏋
鐢熸畺鍣ㄧ柋鐤规偅鑰呰娓匢L-8銆両L-12銆乀NF-伪銆両FN-纬姘村钩鐨勭爺绌
鐢熸畺鍣ㄧ柋鐤规偅鑰呮哀鍖栧簲婵涓庣粏鑳炲厤鐤姸鎬佺殑鐮旂┒
閭撲簯鍗,鏉ㄤ笢浜,涓囨矏鑺,闄堝叴骞,闄堟槧鐜; 澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呭鍛ㄨIL-12涓嶵h1/Th2缁嗚優鍥犲瓙鐨勬娴
杩5骞存潵涓尰鑽不鐤楃敓娈栧櫒鐤辩柟鐨勮繘灞
澶嶅彂鎬х敓娈栧櫒鐤辩柟鎮ｈ呯殑蹇冪悊鍋ュ悍鐘跺喌鍜屽績鐞嗘姢鐞
80渚嬮璇婄敓娈栧櫒鐤辩柟鍙婂叾閰嶅伓鐢熸畺鍣ㄧ柋鐤瑰彂灞曟儏鍐靛垎鏋 [J];宀崡鐨偆鎬х梾绉戞潅蹇; 2005骞01鏈; 37-38
[J];浜戝崡涓尰涓嵂鏉傚織; 2002骞03鏈; 5
[J];涓浗瀹炵敤涔℃潙鍖荤敓鏉傚織; 2004骞05鏈; 14-15
鏅氭湡濡婂涓啀鍙戞х敓娈栧櫒鐤辩柟鐨勭梾姣掑绛涢 [J];鍥介檯妫楠屽尰瀛︽潅蹇; 1987骞05鏈; 40
[J];鐨偆鐥呬笌鎬х梾; 2006骞04鏈; 51-52
[J];瀹跺涵鍖诲; 2002骞03鏈; 56
[J];瀹跺涵鍖昏嵂; 2005骞10鏈; 43
[J];鐨偆鐥呬笌鎬х梾; 2001骞03鏈; 19-21
104渚嬬敓娈栧櫒鐤辩柟鎮ｈ呮祦琛岀梾瀛︾壒寰佸垎鏋 [J];涓浗楹婚鐨偆鐥呮潅蹇; 2005骞02鏈; 38-39
[J];涓浗鍖诲垔; 1999骞12鏈; 12
鐢熸畺鍣ㄧ柋鐤规偅鑰呯殑姘у寲搴旀縺涓庣粏鑳炲厤鐤姸鎬佺爺绌
榛勭櫧娑叉不鐤楀鍙戞х敓娈栧櫒鐤辩柟鐨勪复搴婂強瀹為獙鐮旂┒
灏栭攼婀跨枺鎮ｈ呭鍛ㄨT娣嬪反缁嗚優浜氱兢涓庣毊鎹熷眬閮ㄧ粏鑳炲厤鐤姛鑳界殑鐩稿叧鎬х爺绌
姊呮瘨鎮ｈ呯粏鑳炲厤鐤姛鑳界殑妫娴嬪強鍏朵复搴婃剰涔
灏栭攼婀跨枺鎮ｈ呭厤鐤姛鑳界殑鐮旂┒鍙婂厤鐤不鐤楄繘灞
鐜懓绯犵柟鎮ｈ呰娓呬腑IL-2銆両L-10鍜孖FN纬姘村钩鐨勭爺绌
涓タ鍖荤粨鍚堟不鐤楃敓娈栧櫒鐤辩柟140渚嬬枟鏁堣瀵 [A];2002涓浗涓タ鍖荤粨鍚堢毊鑲ゆх梾瀛︽湳浼氳璁烘枃姹囩紪 [C]; 2002骞
鏋楅湱,鍙跺叴涓,寮犺帀,棰滄櫙鍏,鎴村悜鍐; [A];2003涓浗涓タ鍖荤粨鍚堢毊鑲ゆх梾瀛︽湳浼氳璁烘枃姹囩紪 [C]; 2003骞
[A];绗簩娆″叏鍥戒腑瑗垮尰缁撳悎鐢风瀛︽湳浼氳璁烘枃闆 [C]; 2003骞
鎹锋姎(伪鈥2b骞叉壈绱犲柗闆惧墏)棰勯槻鐢熸畺鍣ㄧ柋鐤瑰鍙戠殑鐤楁晥瑙傚療 [A];姹熻タ鐪佺浜旀涓タ鍖荤粨鍚堢毊鑲ょ瀛︽湳浜ゆ祦浼氳鏂囬泦 [C]; 2006骞
涓界彔濞佹姂鍒剁枟娉曢闃茬敓娈栧櫒鐤辩柟澶嶅彂鐨勮瀵 [A];2003涓浗涓タ鍖荤粨鍚堢毊鑲ゆх梾瀛︽湳浼氳璁烘枃姹囩紪 [C]; 2003骞
骞叉壈绱犳不鐤楀甫鐘剁柋鐤34渚嬬枟鏁堝強鍏嶇柅鍔熻兘瑙傚療 [A];涓崕鍖诲浼氱鍗佷簩娆″叏鍥界毊鑲ゆх梾瀛︽湳浼氳璁烘枃闆 [C]; 2006骞
65渚嬪コ鎬х敓娈栧櫒婧冪枴绯滅儌鎬х柧鐥呯梾鍥犲強涓村簥鍒嗘瀽 [A];2002涓浗涓タ鍖荤粨鍚堢毊鑲ゆх梾瀛︽湳浼氳璁烘枃姹囩紪 [C]; 2002骞
涓囦箖娲涢煢娌荤枟澶嶅彂鎬х敓娈栧櫒鐤辩柟涓嶅悓鐤楃▼瀵规瘮鐮旂┒ [A];2001骞翠腑鍥戒腑瑗垮尰缁撳悎鐨偆鎬х梾瀛︽湳浼氳璁烘枃姹囩紪 [C]; 2001骞
鐗圭害鐨偆绉 涓讳换鍖诲笀 鍒樺織鍒;
浜掕仈缃戝嚭鐗堣鍙瘉鏂板嚭缃戣瘉锛堜含锛夊瓧008鍙
鍞崱鐑嚎锛800-810-6613銆010-62789720銆010-62773682
鍞悗鏈嶅姟锛800-810-1436(闄愬骇鏈烘嫧鎵) 010-62791813銆010-62783978
鎷涘晢鐑嚎锛 010-62772106 鎶曡瘔鐢佃瘽锛010-62791994 2007 涓浗鐭ョ綉(cnki)鐭ョ綉绌洪棿,鐢熸畺鍣ㄧ柋鐤圭殑缁嗚優鍏嶇柅鍙婂厤鐤不鐤楃幇鐘,鐢熸畺鍣ㄧ柋鐤,缁嗚優鍏嶇柅,鍏嶇柅娌荤枟 生殖器疱疹

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